Table 2.
Probability of death in subgroups and risk factors in dialysis patients with COVID-19
| n | Probability of death within 28 days (95% CI) |
Hazard ratio (95% CI) |
|||
|---|---|---|---|---|---|
| Crude | Adjusteda | Crude | Adjusteda | ||
| Age at COVID-19 diagnosis, yr | |||||
| 0–64 | 1088 | 8.9 (7.2–10.8) | 8.7 (6.9–10.4) | 1 | 1 |
| 65–74 | 857 | 20.8 (18.1–23.8) | 20.0 (17.2–22.7) | 2.59 (2.00–3.35) | 2.54 (1.96–3.29) |
| ≥75 | 1340 | 31.4 (28.9–34.0) | 29.1 (26.5–31.7) | 4.10 (3.26–5.16) | 3.85 (3.06–4.86) |
| Sex | |||||
| Female | 1208 | 19.0 (16.8–21.5) | 16.0 (13.9–18.1) | 1 | 1 |
| Male | 2077 | 22.5 (20.7–24.4) | 19.2 (17.3–21.0) | 1.21 (1.03–1.43) | 1.23 (1.04–1.45) |
| Primary renal disease | |||||
| Glomerulonephritis | 381 | 16.7 (13.2–21.0) | 16.4 (12.4–20.2) | 1 | 1 |
| Diabetes | 839 | 20.6 (17.9–23.6) | 17.8 (15.1–20.4) | 1.28 (0.95–1.72) | 1.11 (0.82–1.49) |
| Hypertension/RVD | 695 | 24.3 (21.2–27.8) | 19.4 (16.4–22.3) | 1.55 (1.15–2.08) | 1.22 (0.90–1.65) |
| Other | 1370 | 21.2 (19.1–23.6) | 17.7 (15.5–19.8) | 1.33 (1.01–1.77) | 1.11 (0.84–1.48) |
| Year of KRT startb | |||||
| <2014 | 803 | 20.8 (18.0–23.9) | 19.0 (16.1–21.9) | 1.05 (0.86–1.28) | 1.13 (0.92–1.39) |
| 2014–2017 | 1128 | 22.8 (20.4–25.4) | 17.9 (15.5–20.2) | 1.08 (0.99–1.17) | 1.02 (0.94–1.12) |
| 2018–2020 | 1354 | 20.1 (18.0–22.4) | 17.3 (15.1–19.5) | 1 | 1 |
| Treatment modality | |||||
| HD | 3160 | 21.0 (19.6–22.6) | 18.0 (16.3–19.7) | 1 | 1 |
| PD | 125 | 25.0 (18.2–33.9) | 21.6 (14.1–28.5) | 1.23 (0.85–1.77) | 1.24 (0.85–1.80) |
| Country | |||||
| Austria | 44 | 25.0 (14.7–40.6) | 21.7 (9.4–32.4) | 0.87 (0.43–1.78) | 0.89 (0.43–1.81) |
| Belgium (French-speaking part) | 140 | 21.2 (15.0–29.5) | 20.3 (12.9–27.0) | 0.66 (0.38–1.15) | 0.71 (0.41–1.23) |
| France | 1631 | 17.6 (15.8–19.6) | 15.6 (13.6–17.5) | 0.57 (0.38–0.87) | 0.58 (0.38–0.88) |
| Romania | 270 | 8.5 (5.3–13.6) | 10.4 (5.4–15.2) | 0.27 (0.14–0.49) | 0.38 (0.21–0.71) |
| Spain | 976 | 27.8 (25.0–30.7) | 24.2 (21.0.2–27.1) | 0.93 (0.61–1.42) | 0.91 (0.60–1.39) |
| Switzerland | 87 | 28.8 (20.3–39.9) | 25.0 (15.5–33.4) | 1 | 1 |
| The Netherlands | 137 | 29.7 (22.6–38.3) | 25.7 (18.1–32.6) | 1.06 (0.64–1.76) | 1.06 (0.64–1.76) |
CI, confidence interval; COVID-19, coronavirus disease 2019; HD, hemodialysis; KRT, kidney replacement therapy; PD, peritoneal dialysis; RVD, renovascular disease.
a
The model for age was adjusted for sex and country; the model for sex was adjusted for age and country; the model for primary renal disease (PRD) was adjusted for age, sex, and country; the model for year of KRT start was adjusted for age, sex, PRD, and country; the model for treatment modality was adjusted for age, sex, PRD, year of KRT start, and country; and the model for country was adjusted for age, sex, PRD, and year of KRT start.
b
For Spain this was year of dialysis start.