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. 2020 Sep 16;13(18):4108. doi: 10.3390/ma13184108

Table 1.

Overview of natural biomaterials related to plastic surgery.

Name Source Application Mode Application Site Advantages Disadvantages
Natural Biomaterials
Bio-protein glue [15,16,17,18] Blood from animals Injectable liquid Hemostasis of venule hemorrhage in burn patients Good biocompatibility The application range is narrow
Decellularized tissue [19,20,21,22,23,24,25,26] Dermis, valve, and other tissue from human or animals Biological patch Skin transplantation in burn patients Good biocompatibility High cost
Collagen [27,28] Connective tissue of animals, such as bovine achilles tendon Injectable liquid Facial soft tissue filler for crow’s feet, periorbital wrinkles, and deep scars Good biocompatibility; can interact with cells; good mechanical properties; moisture retention; low immunogenicity; biodegradability Rejection reaction; possible disease transfection
HA [29,30,31,32,33,34,35,36] cockscomb, umbilical cord, eyeballs, and cartilage Injectable liquid Fillers for wrinkles of the decree lines, corners of the mouth, forehead, eyebrows, nose, lips, chin, acne, and chickenpox crypt scar Minimal rejection reaction Mild swelling; rapid degradation

HA: Hyaluronic acid.