. 2020 Sep 16;8(3):69. doi: 10.3390/toxics8030069

Table 1.

Left and right ventricular pressure of rats during intravenous continuous administration of epinephrine and/or norepinephrine.

Parameters	Ventricular Pressure (mmHg)
Parameters	Hour	Sham (n = 7)	E (n = 7)	NE (n = 7)	E+NE (n = 8)
LVSP	0 h	86.2 ± 11.1	90.3 ± 9.7	89.0 ± 11.1	87.0 ± 8.7
	1 h	87.8 ± 13.0	122.4 ± 18.7 *^,†	118.4 ± 8.2 *^,†	118.4 ± 16.4 *^,†
	3 h	95.2 ± 10.0 ^†,‡	114.0 ± 20.3 *^,†	112.4 ± 11.5 *^,†	104.4 ± 16.9 ^†,‡
	6 h	100.5 ± 14.21^†,‡,§	111.1 ± 24.4 ^†	119.3 ± 17.7 ^†	95.1 ± 12.9 ^‡,§,^¥
LVEDP	0 h	11.9 ± 5.1	9.0 ± 2.8	11.8 ± 6.0	11.0 ± 3.9
	1 h	12.3 ± 5.5	16.7 ± 12.5 ^†	19.9 ± 15.1	20.8 ± 8.3 *^,†
	3 h	11.2 ± 5.6	14.4 ± 9.5	16.7 ± 11.8	15.2 ± 7.2 ^‡
	6 h	12.3 ± 7.1	13.1 ± 7.2	17.2 ± 11.3	13.3 ± 5.2 ^‡
RVSP	0 h	17.2 ± 3.0	17.3 ± 3.6	16.8 ± 2.5	18.4 ± 3.9
	1 h	18.2 ± 4.2	27.3 ± 5.1 *^,†	27.8 ± 2.1 *^,†	29.8 ± 5.6 *^,†
	3 h	17.9 ± 4.1	28.3 ± 5.1 *^,†	22.9 ± 2.9 *^,†,‡,#	26.4 ± 6.0 *^,†
	6 h	18.8 ± 4.0	21.6 ± 5.3 ^‡,§	19.3 ± 4.9 ^‡	23.0 ± 6.2 ^†,‡,§
RVEDP	0 h	7.3 ± 3.1	8.0 ± 1.6	9.0 ± 4.1	8.1 ± 3.0
	1 h	8.2 ± 3.4	15.4 ± 5.2 *^,†	18.9 ± 4.0 *^,†	15.5 ± 4.5 *^,†
	3 h	8.2 ± 3.5	17.0 ± 5.8 *^,†	15.1 ± 3.1 *^,†	13.2 ± 5.6 *^,†
	6 h	9.2 ± 3.9 ^†	13.2 ± 4.5 ^†,§	12.4 ± 4.1 ^‡	10.2 ± 4.2 ^‡,§

Data are expressed as means ± SD. E, epinephrine group; E+NE, epinephrine and norepinephrine group; LVEDP left ventricular end-diastolic pressure; LVSP, left ventricular systolic pressure; NE, norepinephrine group; RVEDP, right ventricular end-diastolic pressure; RVSP, right ventricular systolic pressure; sham, 0.9% normal saline group. * p < 0.05 vs. sham group. ^† p < 0.05 vs. respective group at 0 h. ^‡ p < 0.05 vs. respective group at 1 h. ^§ p < 0.05 vs. respective group at 3 h. ^# p < 0.05 vs. E group. ^¥ p < 0.05 vs. NE group.