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Viability of astrocytes and neurons after exposure to SiO2-NPs. The neurons and astrocytes were exposed to 0–100 µg/mL SiO2-NPs. (a) Calcein-AM uptake in neurons and astrocytes. (b) MTT reduction in neurons and astrocytes. Data are presented as mean ± SEM of five to six independent experiments with three technical replicates. Statistical analysis was by two-way ANOVA followed by Bonferroni’s post hoc test. *p < 0.05, **p < 0.01, ***p < 0.001 vs. control.
