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. 2020 Oct 13;40(10):BSR20201140. doi: 10.1042/BSR20201140

Figure 5. Gene set enrichment analysis of CRAD targets.

Figure 5

(A) GSEA of the total 1499 Reactome gene sets. (B) GSEA showing enrichment of the Reactome gene sets of Interferon alpha/beta responses and signaling and Caspase activation in the shCRAD group. (C) GSEA showing the enrichment of the Reactome gene sets of DNA replication and cell cycle checkpoint in the shCtrl group. (D) GSEA of 50 Hallmarks gene sets. (E) GSEA showing enrichment of hallmark gene sets interferon-α response and apoptosis in the shCRAD group. (F) GSEA showing enrichment of hallmark gene sets DNA repair and G2/M checkpoint in shCtrl group.