Table 3. Hazard raito (HR)* of lung cancer by level of alcohol consumption according to smoking status.
Never drinkers |
Ever drinkers |
Current drinkers (ethanol intake) | Ex-drinkers | P for trend 1† | P for trend 2‡ | ||||
≤24.9 g/day | 25.0-49.9 g/day | ≥50.0 g/day | |||||||
Never smokers | Person-years | 13,368 | 36,575 | 21,297 | 9,607 | 3,331 | 2,339 | ||
No. of deaths | 5 | 13 | 7 | 1 | 1 | 4 | |||
HR | 1.00 | 1.22 (0.43-3.45) | 1.10 (0.35-3.51) | 0.37 (0.04-3.18) | 1.15 (0.13-9.98) | 4.20 (1.12-15.72) | 0.61 | 0.54 | |
Ex-smokers | Person-years | 10,035 | 50,374 | 24,004 | 16,089 | 4,993 | 5,288 | ||
No. of deaths | 19 | 61 | 27 | 15 | 2 | 17 | |||
HR | 1.00 | 0.74 (0.44-1.25) | 0.64 (0.36-1.16) | 0.67 (0.34-1.33) | 0.34 (0.08-1.47) | 1.37 (0.71-2.64) | 0.13 | 0.53 | |
Current smokers (Cigarretes/day) | |||||||||
≤20 | Person-years | 15,227 | 72,388 | 30,626 | 26,672 | 10,579 | 4,510 | ||
No. of deaths | 33 | 110 | 44 | 35 | 16 | 15 | |||
HR | 1.00 | 0.86 (0.58-1.27) | 0.76 (0.48-1.20) | 0.78 (0.48-1.27) | 1.09 (0.59-2.01) | 1.32 (0.72-2.43) | 0.99 | 0.20 | |
>20 | Person-years | 6,509 | 28,142 | 9,425 | 10,140 | 7,084 | 1,493 | ||
No. of deaths | 12 | 57 | 11 | 23 | 13 | 10 | |||
HR | 1.00 | 1.31 (0.69-2.47) | 0.74 (0.33-1.70) | 1.49 (0.73-3.03) | 1.31 (0.58-2.93) | 2.64 (1.13-6.14) | 0.20 | 0.15 |
* : Adjusted for age, family history of lung cancer, intake of green-leafy vegetables, oranges and fruits other than oranges.
† : P for trend among current drinkers. The test for linear trends includes never drinkers.
‡ : P for trend among current drinkers. The test for linear trends excudes never drinkers.
95% confidence intervals in parentheses.