Table 2.
Characteristic |
Univariable analysis |
Multivariable analysis |
||||
---|---|---|---|---|---|---|
Regression coefficient | 95% CI | P | Regression coefficient | 95% CI | P | |
Male (vs female) | 0.048 | –0.039 to 0.136 | .278 | NI | ||
Age (1 y) | –0.001 | –0.005 to 0.002 | .537 | NI | ||
Stage | ||||||
N3 (vs N2 and N1) | –0.085 | –0.206 to 0.037 | .168 | NI | ||
Baseline lymphocyte (109 cells/L) | 0.112 | 0.068-0.156 | <.001 | 0.098 | 0.060-0.135 | <.001 |
Chemotherapy | ||||||
5 courses (vs fewer than 5 courses) | 0.060 | –0.005 to –0.126 | .071 | 0.044 | –0.005 to 0.093 | .081 |
Radiation therapy | ||||||
Log PTV | –0.393 | –0.629 to –0.158 | .001 | –0.205 | –0.399 to –0.011 | .038 |
EDIC | –0.085 | –0.115 to –0.055 | <.001 | –0.061 | –0.089 to –0.034 | <.001 |
IMRT (vs 3DCRT) | 0.019 | –0.047 to 0.084 | .567 | NI |
Abbreviations: 3DCRT = 3-dimensional conformal radiation therapy; CI = confidence interval; EDIC = effective dose to the circulating immune cells; IMRT = intensity modulated radiation therapy; NI = not included; PTV = planning target volume.