Table 1.
| Parameter | Total (N=271) | TBFB (n=151) | TBCB (n=120) | P valuec |
|---|---|---|---|---|
| Age (y) | 61±14 | 59±14 | 62±14 | .091 |
| Male sex | 143 (53) | 76 (50) | 67 (56) | .37 |
| Smoking history | 91 (34) | 48 (32) | 43 (36) | .51 |
| COPD | 16 (6) | 11 (7) | 5 (4) | .27 |
| Pulmonary hypertensiond | 21 (8) | 17 (12) | 4 (3) | .011 |
| Obstructive sleep apnea | 37 (14) | 24 (16) | 13 (11) | .20 |
| CTD | 46 (17) | 25 (17) | 21 (18) | .90 |
| Renal insufficiency | 5 (2) | 4 (3) | 1 (1) | .26 |
| Body mass index (kg/m2) | 30±7 | 30±8 | 30±6 | .99 |
| Resting Spo2% | 92.5±11 | 94±4 | 91±15 | .22 |
| Supplemental oxygen | 13 (5) | 7 (6) | 6 (5) | .93 |
| FEV1% predicted | 74±20 | 74±20 | 73±21 | .84 |
| FEV1/FVC | 77±12 | 77±11 | 76±12 | .81 |
| FVC% predicted | 77±18 | 78±19 | 75±18 | .27 |
| TLC% predicted | 82±17 | 84±17 | 79±17 | .065 |
| DLCO% predicted (corrected for Hgb) | 64±19 | 65±19 | 51±27 | .20 |
a
COPD = chronic obstructive pulmonary disease; CTD = connective tissue disease; DLCO = single-breath diffusing capacity for carbon monoxide; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity; Hgb = hemoglobin (g/dL); Spo2 = peripheral capillary oxygen saturation; TBCB = transbronchial cryobiopsy; TBFB = transbronchial forceps biopsy; TLC = total lung capacity.
b
Data are presented as mean ± SD for continuous variables or as No. (percentage) for categorical variables.
c
Kruskal-Wallis for continuous variables and χ2 test for categorical variables.
d
Echocardiographic results not available for 62 patients who underwent TBFB (44.9%) and 55 patients who underwent TBCB (47.4%).