. 2020 Oct 6;4(5):565–574. doi: 10.1016/j.mayocpiqo.2020.05.005

Table 5.

Comparative Outcomes Adjusted by Prebiopsy Clinical and Radiographic Impressions^a^,^b^,^c

	Odds ratio	95% CI	P value
Association with diagnostic yield
TBCB	1.73	1.07-2.83	.026
TBCB adjusted for clinical impression	2.21	1.22-4.08	.010
Association with clinical utility
TBCB	2.21	1.36-3.63	.001
TBCB adjusted for clinical impression	3.23	1.76-6.10	<.001

ILD = interstitial lung disease; IPF = idiopathic pulmonary fibrosis; TBCB = transbronchial cryobiopsy; TBFB = transbronchial forceps biopsy; UIP = usual interstitial pneumonia.

Prebiopsy clinical impressions UIP/IPF, non-IPF fibrotic ILD, and aspiration pneumonitis were associated with TBCB (P=.002, P=.012, and P=.024, respectively). Eosinophilic pneumonia, organizing pneumonia, and infection were associated with TBFB (P=.007, P=.046, and P=.001, respectively).

Radiographic impression “indeterminate UIP” was associated with TBCB, whereas “alternative diagnosis” was associated with TBFB (P=.002).