Table 2.
N | Cases | Person timeb | Incidence rateb | 95% CI | Crude HR | 95% CI | Adjusted HRc | 95% CI | |
---|---|---|---|---|---|---|---|---|---|
Vancomycina | 5449 | 22 | 22.35 | 0.93 | 0.94–1.92 | ||||
Comparators | 27,548 | 107 | 113.93 | 0.96 | 0.77–1.12 | 1.04 | 0.85–1.90 | 0.74 | 0.45–1.21 |
Cefazolin | 20,124 | 58 | 83.31 | 0.69 | 0.53–0.89 | 1.40 | 0.86–2.29 | 1.01 | 0.55–1.83 |
Linezolid | 251 | 6 | 1.03 | 5.76 | 2.59–12.83 | 0.17 | 0.07–0.42 | 0.17 | 0.01–0.46 |
Piperacillin | 3885 | 25 | 16.00 | 1.54 | 1.04–2.28 | 0.63 | 0.35–1.11 | 0.47 | 0.24–0.91 |
Cefepime | 433 | 2 | 1.79 | 1.11 | 0.28–4.43 | 0.87 | 0.45–3.70 | 0.80 | 0.19–3.69 |
Meropenem | 379 | 7 | 1.58 | 4.44 | 2.12–9.32 | 0.22 | 0.09–0.51 | 0.21 | 0.10–0.52 |
Ertapenem | 2205 | 8 | 9.13 | 0.86 | 0.43–1.73 | 1.11 | 0.51–2.50 | 0.47 | 0.19–1.17 |
Daptomycin | 271 | 1 | 1.12 | 0.88 | 0.12–6.25 | 1.09 | 0.15–8.11 | 0.99 | 0.12–8.19 |
95% CI 95% confidence interval, HR hazard ratio.
aIndex group.
bPer 10 person-years.
cAdjusted for age, gender, medical history, co-medication, type of surgery, main diagnosis (not Included in model because of low cell count: vancomycin vs. piperacillin ,vancomycin vs. ertapenem, vancomycin vs. daptomycin, and vancomycin vs. cefepime).