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. 2020 Oct 14;10:17282. doi: 10.1038/s41598-020-73687-9

Table 2.

Incidence rates and hazard ratios of vancomycin compared to all comparators and vancomycin compared to singular comparator.

N Cases Person timeb Incidence rateb 95% CI Crude HR 95% CI Adjusted HRc 95% CI
Vancomycina 5449 22 22.35 0.93 0.94–1.92
Comparators 27,548 107 113.93 0.96 0.77–1.12 1.04 0.85–1.90 0.74 0.45–1.21
Cefazolin 20,124 58 83.31 0.69 0.53–0.89 1.40 0.86–2.29 1.01 0.55–1.83
Linezolid 251 6 1.03 5.76 2.59–12.83 0.17 0.07–0.42 0.17 0.01–0.46
Piperacillin 3885 25 16.00 1.54 1.04–2.28 0.63 0.35–1.11 0.47 0.24–0.91
Cefepime 433 2 1.79 1.11 0.28–4.43 0.87 0.45–3.70 0.80 0.19–3.69
Meropenem 379 7 1.58 4.44 2.12–9.32 0.22 0.09–0.51 0.21 0.10–0.52
Ertapenem 2205 8 9.13 0.86 0.43–1.73 1.11 0.51–2.50 0.47 0.19–1.17
Daptomycin 271 1 1.12 0.88 0.12–6.25 1.09 0.15–8.11 0.99 0.12–8.19

95% CI 95% confidence interval, HR hazard ratio.

aIndex group.

bPer 10 person-years.

cAdjusted for age, gender, medical history, co-medication, type of surgery, main diagnosis (not Included in model because of low cell count: vancomycin vs. piperacillin ,vancomycin vs. ertapenem, vancomycin vs. daptomycin, and vancomycin vs. cefepime).