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. 2020 Oct 14;10:17282. doi: 10.1038/s41598-020-73687-9

Table 3.

Incidence rates and hazard ratios of vancomycin compared to all comparators stratified for antibiotic treatment duration.

N Cases Person timeb Incidence rateb 95% CI Crude HR 95% CI Adjusted HRc 95% CI
< 7 days of treatment
Vancomycina 4347 8 18.25 0.44 0.22–0.88
Comparators 23,965 72 100.67 0.72 0.57–0.90 0.61 0.30–1.27 0.49 0.22–1.08
7 to 14 days of treatment
Vancomycina 871 9 3.64 2.47 1.28–4.75
Comparators 2845 23 11.88 1,94 1.29–2.91 1.28 0.59–2.76 0.89 0.37–2.12
> 14 days of treatment
Vancomycina 231 5 0.96 5.19 2.16–12.48
Comparators 738 12 3.08 3.89 2.21–6.86 1.34 0.47–3.79 0.89 0.26–3.10

95% CI 95% confidence interval, HR hazard ratio.

aIndex group.

bPer 10 person-years.

cAdjusted for age, gender, medical history, co-medication, type of surgery, main diagnosis;