Table 7.
Docking score of tyrosine kinase (interacting amino acid).
| Active constituents | Docking Score of tyrosine kinase (interacting amino acid) | ||||
|---|---|---|---|---|---|
| c-Met (PDB ID: 5EYD) | EGFR (PDB ID: 4ZAU) | PDGFR α/β (PDB ID: 5GRN) | VEGFR family (PDB ID:2OH4) | ERR (PDB ID: 1ERR-α) | |
| Catechin | − 6.6651 (TYR 1230) | − 7.969 (GLU 762) | − 10.392 (PHE 837) | − 7.793 (CYS 917) | − 9.533 (MET 421) |
| Cyaniding | − 7.315 (ARG 1208) | − 7.747 (GLU 762) | − 10.302 (GLU 644) | − 11.233 (LEU 838) | − 9.895 (LEU 346) |
| Ellagic acid | − 7.348 (GLY 1163) | − 5.792 (MET 793) | − 4.396 (VAL 815) | − 4.727 (ARG 1025) | − 8.197 (LEU 346) |
| Quercetin | − 7.576 (ALA 1221) | − 7.417 (GLU 762) | − 10.056 (LEU 599) | − 10.224 (CYS 917) | − 9.378 (GLU 353) |
Bold signifies that among each class of tyrosine kinase the maximum score of the active component.