Fig. 2.

Data mining identification of compounds potentially involved in the regulation of human receptor ACE2 and proteases of SARS-CoV-2 S protein at mRNA level in human tissues. Data were retrieved from the Comparative Toxicogenomics Database (CTD). Colour code: blue square, the chemical increases gene expression; green square, the chemical decreases gene expression; yellow square, the chemical increases or decreases gene expression depending on studies; white, no regulation reported in the database. The full list of compounds and relationships is reported in Supplementary Table S2. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)