Table 3.
The features with significantly different median (range) values between benign and malignant groups (train set)
| Features | Benign group | Malignant group | p value |
|---|---|---|---|
| SUVmin | 1.8 (1.0–2.7) | 2.3 (1.1–12.1) | 0.008 |
| SUVmean | 2.5 (1.4–7.4) | 3.3 (2.0–19.5) | 0.009 |
| SUVstd | 0.5 (0.2–2.9) | 0.8 (0.3–4.0) | 0.012 |
| SUVmax | 3.7 (2.2–14.7) | 5.6 (2.6–30.4) | 0.004 |
| SUVpeak | 2.9 (1.7–10.3) | 4.3 (2.5–25.4) | 0.01 |
| TLG | 14.8 (7.0–39.7) | 48.1 (6.7–491.2) | < 0.001 |
| HISTO_entropylog10 | 0.53 (0.23–1.22) | 0.67 (0.40–1.42) | 0.039 |
| HISTO_entropylog2 | 1.76 (0.78–4.06) | 2.21 (1.32–4.73) | 0.044 |
| SHAPEvolume | 5.1 (3.3–27.7) | 12.0 (3.1–61.1) | 0.008 |
| SHAPE_sphericity | 1.055 (0.990–1.160) | 1.025 (0.910–1.160) | 0.036 |
| SHAPE_compacity | 0.90 (0.67–1.62) | 1.26 (0.68–3.02) | 0.004 |
| GLCM_entropylog10 | 1.06 (0.45–1.73) | 1.29 (0.72–2.41) | 0.026 |
| GLCM_entropylog2 | 3.53 (1.49–5.76) | 4.28 (2.39–8.00) | 0.024 |
| GLCM_correlation | 0.196 (0.051–0.506) | 0.316 (0.084–0.521) | 0.014 |
| GLRLM_LGRE | 0.046 (0.009–0.107) | 0.026 (0.001–0.067) | 0.008 |
| GLRLM_HGRE | 25.8 (10.4–226.3) | 43.9 (16.7–1355.9) | 0.011 |
| GLRLM_SRLGE | 0.033 (0.009–0.064) | 0.023 (0.001–0.054) | 0.008 |
| GLRLM_SRHGE | 20.15 (5.80–219.40) | 38.00 (12.70–1307.50) | 0.012 |
| GLRLM_LRLGE | 0.090 (0.010–0.805) | 0.046 (0.001–0.155) | 0.022 |
| GLRLM_LRHGE | 62.6 (28.5–253.9) | 85.1 (40.8–1565.1) | 0.006 |
| GLRLM_RLNU | 43.2 (20.0–84.5) | 105.2 (24.7–645.7) | < 0.001 |
| NGLDMcoarseness | 0.074 (0.022–0.131) | 0.030 (0.006–0.118) | 0.001 |
| GLZLM_LGZE | 0.049 (0.010–0.161) | 0.027 (0.001–0.082) | 0.007 |
| GLZLM_HGZE | 25.35 (9.30–230.50) | 47.30 (16.10–1284.60) | 0.008 |
| GLZLM_SZHGE | 5.65 (0.01–151.50) | 15.75 (0.10–932.40) | 0.01 |
| GLZLM_GLNU | 2.3 (1.0–4.2) | 3.7 (1.0–21.4) | 0.001 |
| GLZLM_ZLNU | 1.8 (1.0–15.0) | 3.2 (1.0–92.7) | 0.012 |
SUV, standard uptake value; TLG, total lesion glycolysis; GLCM, gray-level co-occurrence matrix; GLRLM, gray-level run length matrix; NGLDM, neighborhood gray-level different matrix; GLZLM, gray-level zone length matrix; LGRE, low gray-level run emphasis; HGRE, high gray-level run emphasis; SRLGE, short-run low gray-level emphasis; SRGHE, short-run high gray-level emphasis; LRLGE, long-run low gray-level emphasis; LRHGE, long-run high gray-level emphasis; GLNU, gray-level non-uniformity; RLNU, run length non-uniformity; RP, run percentage; LGZE, low gray-level zone emphasis; HGZE, high gray-level zone emphasis; SZHGE, short-zone high gray-level emphasis; ZLNU, zone length non-uniformity