Table 1.

Mean expression of target gene to endogenous control (GAPDH and ACTB) ± SD, relative to control.

Target	Control	Dry eye	UAMC-00050	Vehicle
Palpebral + bulbar conjunctiva
IL-1α	1.00 ± 0.29	1.50 ± 0.49*	0.95 ± 0.43	0.96 ± 0.24
IL-17A	1.00 ± 1.38	4.12 ± 2.20**	0.21 ± 1.50	0.50 ± 1.70
Tryptase	1.00 ± 0.55	1.62 ± 0.44*	1.61 ± 0.64	1.66 ± 0.52*
Matriptase	1.00 ± 0.10	0.98 ± 0.15	1.01 ± 0.21	1.11 ± 0.29
PAR2	1.00 ± 0.06	1.18 ± 0.39	1.10 ± 0.20	1.05 ± 0.26
uPAR	1.00 ± 0.35	1.40 ± 0.32*	1.80 ± 0.16**	2.83 ± 0.25**
Cornea
Tryptase	1.00 ± 0.50	1.59 ± 0.52*	1.58 ± 0.75	2.68 ± 1.01**
Matriptase	1.00 ± 0.19	1.15 ± 0.16	0.89 ± 0.25	0.91 ± 0.23
PAR2	1.00 ± 0.27	1.28 ± 0.19*	1.22 ± 0.21	1.23 ± 0.15
uPAR	1.00 ± 0.47	1.22 ± 0.52	1.65 ± 0.40*	1.47 ± 0.45

N = 8, comparative qRT-PCR.

*p < 0.05, **p < 0.01 versus control.