Table 3.
Multivariable linear regression analyses.
1. Prediction model of PDSS difference (from preop. to 12 months) | 2. Covariance model of PDSS difference (from preop. to 12 months) | ||
---|---|---|---|
Preoperative | B-coefficient (S.E.) | Difference from preoperative to 12 months | B-coefficient (S.E.) |
Scopa-Aut | 0.471 (0.381) | Scopa-Aut | −0.893 (0.481) |
PDQ-39 | −0.521 (0.325) | PDQ-39 | −0.213 (0.312) |
MDS-UPDRS II | 0.331 (0.554) | MDS-UPDRS II | −0.574 (0.456) |
MDS-UPDRS III off | −0.237 (0.238) | MDS-UPDRS III off | −0.095 (0.245) |
LEDD | −0.237 (0.238) | LEDD | −0.005 (0.007) |
Model fit: | |||
R square adjusted | 1% | 8% | |
(p value) | (0.468) | (0.135) |
1. Prediction model of Scopa-Aut difference (from preop. to 12 months) | 2. Covariance model of Scopa-Aut difference (from preop. to 12 months) | ||
---|---|---|---|
Preoperative | B-coefficient (S.E.) | Difference from preoperative to 12 months | B-coefficient (S.E.) |
PDSS | −0.021 (0.063) | PDSS | −0.081 (0.048) |
PDQ-39 | 0.043 (0.121) | PDQ-39 | 0.308 (0.085)a |
MDS-UPDRS I | −0.086 (0.205) | MDS-UPDRS I | 0.145 (0.212) |
MDS-UPDRS II | 0.048 (0.170) | MDS-UPDRS II | −0.132 (0.154) |
LEDD | 0.003 (0.002) | LEDD | 0.002 (0.002) |
Model fit: | |||
R square adjusted | 3% | 31% | |
(p value) | (0.590) | (<0.001)a |
Dependent variables are the differences in Parkinson’s Disease Sleep Scale (PDSS) and Scopa-Aut total scores from preoperative to 12 months of STN-DBS. As independent variables, preoperative scores are used in the prediction models (1, left column) and differences in scores from preoperative to 12 months in the covariance models (2, right column).
PDQ-39 Parkinson’s Disease Questionnaire-39, LEDD Levodopa equivalent daily doses, MDS-UPDRS Movement Disorder Society revision of the Unified Parkinson’s Disease Rating Scale.
aSignificant (p < 0.05).