Table 1.
Characteristics and Outcomes of Suspected VAP Patient Cohort
| Characteristics | Suspected VAP Cohort (n = 194) | With Probable Aspergillus Infection (n = 24) | Without Probable Aspergillus Infection (n = 170) | P Value |
|---|---|---|---|---|
| Age, median (IQR), yr | 57 (44–69) | 66.5 (49.8-72.5) | 56 (43–69) | 0.07 |
| Sex, M, n (%) | 137 (70.6) | 15 (62.5) | 122 (71.8) | 0.35 |
| APACHE II score on admission, mean (SD) | 17.93 (7.5) | 19.25 (7.5) | 17.74 (7.7) | 0.36 |
| Medical reason for admission, n (%) | 113 (58.2) | 17 (70.9) | 96 (56.5) | 0.18 |
| Surgical reason for admission, n (%) | 81 (41.8) | 7 (29.1) | 74 (43.5) | 0.18 |
| Preenrollment length of stay, median (IQR), d | 7 (4–11) | 7.5 (7–12) | 6 (4–10.75) | 0.19 |
| Steroids, n (%) | 33 (16.9) | 6 (25) | 27 (15.8) | 0.27 |
| WCC on day of BAL, n | 15.3 | 14.95 | 15.3 | 0.83 |
| Renal replacement therapy, n (%) | 16 (8.3) | 3 (12.5) | 13 (7.7) | 0.42 |
| Vasopressors, n (%) | 61 (31.4) | 8 (33.3) | 53 (31.2) | 0.83 |
| Microbiologically confirmed VAP, n (%) | 78 (40.2) | 9 (37.5) | 69 (40.6) | 0.77 |
| Length of stay in critical care, median (IQR), d | 17 (11–31.5) | 25.5 (17.25–32.8) | 15 (10–30.5) | 0.02 |
| Length of stay in hospital, median (IQR), d | 34 (17–62) | 34 (24.5-61) | 34 (14.25–62) | 0.39 |
| ICU mortality, n (%) | 47 (24.1) | 8 (33.3) | 39 (22.8) | 0.27 |
Definition of abbreviations: APACHE II = Acute Physiology and Chronic Evaluation II; IQR = interquartile range; VAP = ventilator-associated pneumonia; WCC = white cell count.