Table 3.

The Effect of Isoniazid Preventive Therapy on Disease Incidence of Children 5 Years of Age or Younger (Complete Data Set)^*

Isoniazid Preventive Therapy	Isoniazid Sensitive		MDR		Mono–Isoniazid Resistant
	Cases/Person-Year	HR (95% CI)	Cases/Person-Year	HR (95% CI)	Cases/Person-Year	HR (95% CI)
No	19/566	Ref	10/145	Ref	3/58	Ref
Yes	9/785	0.28 (0.12–0.58)	2/144	0.19 (0.04–0.98)	1/90	0.25 (0.02–2.76)

Definition of abbreviations: CI = confidence interval; HR = hazard ratio; INH = isoniazid; MDR = multidrug resistant; Ref = reference.

^*Stratified by INH profiles of index cases and adjusted for index case age, recreational drug use, household contact age, sex, bacillus Calmette-Guérin vaccination scar, nutritional status, being a student or not, tuberculosis history, household socioeconomic status, and household residential district

Likelihood ratio test for interaction term = 0.413.