Figure 2.

Voluntary interactions of daily handled mice with the handler before and after the handling session in the course of the initial handling. Left: explorative and positive behaviours (sniffing, touching, climbing). Right: defensive burrowing behaviour. N = 16, Data are represented as means ± SEM. *Differences of exploratory behaviours; s: sniffing approaches s < 0.05; t: touching approaches t < 0.05, tt < 0.01, ttt < 0.001; c: climbing approaches c < 0.05, cc < 0.01, ccc < 0.001; $: differences between pre and post handling.