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. 2020 Oct 14;10:17289. doi: 10.1038/s41598-020-74069-x

Figure 2.

Figure 2

Increasing perfusate Na+ depresses LVDP, independent of changes in flow rate or heart rate. (A) Representative paired left ventricular (LV) pressure traces from a single heart during 145 mM [Na+]o (145 Na+) and 155 mM [Na+]o (155 Na+) perfusion. (B) LVDP was significantly reduced in paired comparisons during perfusion with 155 relative to 145 mM [Na+]o. (C) Flow rate was not significantly reduced when hearts were perfused with 155 relative to 145 mM [Na+]o. (D) Heart rate did not significantly change when varying [Na+]o during baseline conditions. n = 5, *Indicates p < 0.05 as determined by paired Student’s t-test.