Table 1.
Results from two-way ANOVA statistical analysis for all data sets.
| Figure # | Measurement (units) | Sex (male/female) | Surgery | Interaction | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| dfn, dfd | F | p | dfn, dfd | F | p | dfn, dfd | F | p | ||
| Figure 1B | Palpebral opening | 1, 66 | 7.224 | < 0.0091 | 2, 66 | 59.69 | < 0.0001 | 2, 66 | 5.977 | < 0.0041 |
| Figure 3A | Eye wipe | 1, 64 | 7.674 | < 0.0073 | 2, 64 | 3.074 | < 0.0473 | 2, 64 | 4.039 | < 0.00223 |
| Figure 3B | Palpebral opening | 1, 66 | 5.539 | < 0.0216 | 2, 66 | 3.687 | < 0.0304 | 2, 66 | 1.989 | < 0.1449 |
| Figure 5B | Time open arms (%) | 1, 93 | 9.433 | < 0.0028 | 2, 93 | 11.63 | < 0.0001 | 2, 93 | 1.843 | < 0.1640 |
| Figure 5C | Time closed arms (%) | 1, 93 | 6.863 | < 0.0103 | 2, 93 | 19.3 | < 0.0001 | 2, 93 | 1.718 | < 0.1851 |
| Figure 6B | Sholl intersections (subbasal) | 1, 24 | 1.681 | < 0.2071 | 1, 24 | 3.092 | < 0.0914 | 1, 24 | 0.1292 | < 0.7225 |
| Figure 6B | Sholl intersections (terminals) | 1, 24 | 0.2858 | < 0.5978 | 1, 24 | 1.171 | < 0.2900 | 1, 24 | 0.2024 | < 0.6568 |
| Figure 6C | Pixel density (subbasal) | 1, 24 | 3.842 | < 0.0648 | 1, 24 | 0.6278 | < 0.4379 | 1, 24 | 2.072 | < 0.1663 |
| Figure 6C | Pixel density (terminals) | 1, 24 | 0.002819 | < 0.9581 | 1, 24 | 0.8080 | < 0.3777 | 1, 24 | 0.1608 | < 0.6920 |
| Figure 6D | Tears (mm) | 1, 33 | 1.303 | < 0.2619 | 1, 33 | 137.1 | < 0.0001 | 1, 33 | 0.0398 | < 0.8429 |
| Side (ipsi/contra) | Surgery | Interaction | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Figure 1C | Palpebral opening | 1, 66 | 18.65 | < 0.0001 | 2, 66 | 15.546 | < 0.0001 | 2, 66 | 5.639 | < 0.0055 |
| Figure 1D | Palpebral opening | 1, 66 | 38.97 | < 0.0001 | 2, 66 | 64.81 | < 0.0001 | 2, 66 | 41.81 | < 0.0001 |
The two independent factors included surgery (sham, single lacrimal gland excision, double lacrimal gland excision) and either sex (male, female) or side (ipsi- or contralateral to side of surgery)
Dfn degrees of freedom numerator, dfd degrees of freedom denominator, F F statistic, p p-value.