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. 2020 Oct 14;10:17225. doi: 10.1038/s41598-020-73945-w

Table 1.

Results from two-way ANOVA statistical analysis for all data sets.

Figure # Measurement (units) Sex (male/female) Surgery Interaction
dfn, dfd F p dfn, dfd F p dfn, dfd F p
Figure 1B Palpebral opening 1, 66 7.224 < 0.0091 2, 66 59.69 < 0.0001 2, 66 5.977 < 0.0041
Figure 3A Eye wipe 1, 64 7.674 < 0.0073 2, 64 3.074 < 0.0473 2, 64 4.039 < 0.00223
Figure 3B Palpebral opening 1, 66 5.539 < 0.0216 2, 66 3.687 < 0.0304 2, 66 1.989 < 0.1449
Figure 5B Time open arms (%) 1, 93 9.433 < 0.0028 2, 93 11.63 < 0.0001 2, 93 1.843 < 0.1640
Figure 5C Time closed arms (%) 1, 93 6.863 < 0.0103 2, 93 19.3 < 0.0001 2, 93 1.718 < 0.1851
Figure 6B Sholl intersections (subbasal) 1, 24 1.681 < 0.2071 1, 24 3.092 < 0.0914 1, 24 0.1292 < 0.7225
Figure 6B Sholl intersections (terminals) 1, 24 0.2858 < 0.5978 1, 24 1.171 < 0.2900 1, 24 0.2024 < 0.6568
Figure 6C Pixel density (subbasal) 1, 24 3.842 < 0.0648 1, 24 0.6278 < 0.4379 1, 24 2.072 < 0.1663
Figure 6C Pixel density (terminals) 1, 24 0.002819 < 0.9581 1, 24 0.8080 < 0.3777 1, 24 0.1608 < 0.6920
Figure 6D Tears (mm) 1, 33 1.303 < 0.2619 1, 33 137.1 < 0.0001 1, 33 0.0398 < 0.8429
Side (ipsi/contra) Surgery Interaction
Figure 1C Palpebral opening 1, 66 18.65 < 0.0001 2, 66 15.546 < 0.0001 2, 66 5.639 < 0.0055
Figure 1D Palpebral opening 1, 66 38.97 < 0.0001 2, 66 64.81 < 0.0001 2, 66 41.81 < 0.0001

The two independent factors included surgery (sham, single lacrimal gland excision, double lacrimal gland excision) and either sex (male, female) or side (ipsi- or contralateral to side of surgery)

Dfn degrees of freedom numerator, dfd degrees of freedom denominator, F F statistic, p p-value.