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. 2020 Sep 26;88(8):662–673. doi: 10.1007/s00239-020-09965-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Alignment of examples of each subfamily alongside bacterial orthologues for each (aside from CPD III which is characterised from the bacteria A. tumefaciens and from Plant Photolyase A. thaliana which has no bacterial orthologues). Residues involved in substrate recognition are highlighted with a black box and whole conserved residues are shown with an *. Sequences used are X. laevis (6–4) PL (NP_001081421.1), X. laevis CPD II (NP_001089127.1), X. laevis CD (NP_001084438.1), Geobacter sulfurreducens CPD II (WP_010943456.1), Agrobacterium tumificans (WP_010971478.1), A. thaliana Cry1 (NP_567341.1), A. thaliana PHR2 (NP_182281.1), X. axonpodis (WP_011050942.1), V. alfalfae (XP_002999933.1), Cronobacter sakazakii WP_012125345.1, H. sapiens Cry1 (NP_004066.1), G. kilaueensis (WP_023172734.1), Synechocystis PCC 6803 CD (WP_014407097.1) (Color figure online)