Table 6:

Uncomplicated Malaria Treatment

Generic Name	Dose Regimen
Chloroquine Hydroxychloroquine	• 600mg base (1000mg salt) PO as initial dose  • 300mg base (500mg salt) PO at 6,24, and 48 hours after initial dose  • Total dose: 1500mg base (2000mg salt)  • ________________________________________________________  • 620mg base (800mg salt) PO as initial dose  • 310mg base (400mg salt) PO at 6,24, and 48 hours after initial dose  • Total dose: 1550mg base (2000mg salt)
Mefloquine	• 684 mg base (750 mg salt) PO as initial dose  • 456 mg base (500 mg salt) PO given 6–12 hours after initial dose  •Total dose= 1,250 mg salt
Quinine Sulfate and Clindamycin	Quinine Sulfate  • 542mg base (650mg salt) PO TID for 3 or 7 days  • For infections acquired in Southeast Asia take quinine for 7 days. All other take for, 3 days. Clindamycin  • 20mg base/kg/day PO divided into TID dosing for 7 days
Artemether-lumefantrine	• 1 tablet = 20mg artemether and 120 mg lumefantrine  • 4 tablets = 1 dose  • 3-day treatment schedule with a total of 6 oral doses  • The patient should receive the initial dose, followed by the second dose 8 hours later, then 1 dose PO BID for the following 2 days.

Adapted from CDC Guidelines¹¹.