. Author manuscript; available in PMC: 2020 Oct 15.

Published in final edited form as: Cell Mol Bioeng. 2014 Jul 6;7(3):446–459. doi: 10.1007/s12195-014-0344-9

TABLE 2.

List of active variables.

Variable name	Description
B1on	Amount of activated β1 integrin as a fraction of total
B3on	Amount of activated β3 integrin as a fraction of total
TBRT	TGF-β1 receptor (TβR2) with TGF-β1 ligand attached
pTBR2	Phosphorylated and ligand bound TGF-β1 receptor (TβR2)
pS	Activated Src kinase
pFAK	FAK phosphorylated on tyrosine 397
3pF	FAK phosphorylated on tyrosines in 400–900 range with active kinase activity
pP	Active p38
pE	Active ERK

The total amount of each protein is conserved and given a value of 1, so the inactive species fraction is calculated at each time point as 1 − Σ (active protein species).