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. Author manuscript; available in PMC: 2020 Oct 15.
Published in final edited form as: Cell Mol Bioeng. 2014 Jul 6;7(3):446–459. doi: 10.1007/s12195-014-0344-9

TABLE 4.

Model comparison and statistical analysis.

Model Features MSE χ2 ΔAIC
01 No Src dependency or Src feedback or ERK feedback 3.92 1700 22.6
02 No Src dependency term, but Src and ERK feedback 0.53   234   5.97
03* Src dependency and Src feedback 0.056     16.5   0
04 Src dependency, Src and ERK feedback 0.173     42.2   1.68
05 Model 04 without stiffness dependence of IpP 0.179     60.2   1.76
06 Model 04 with β3 integrin positive feedback 0.169     42.4     3.63
07* Model 03 with calpain negative feedback to ERK 0.0363     21.9   3.7
08 Model 04 with no p3F activation of p38 0.190     45.3   1.68
*

Indicates that the χ2 value for the given model has a p < 0.05 for a χ2 distribution with 15 degrees of freedom, indicating that the model predictions are not significantly different from the experimental data set.