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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Bioorg Chem. 2019 Dec 20;95:103523. doi: 10.1016/j.bioorg.2019.103523

Table 2.

Potency of select taxoids against MCF-7/PTX cell line [60].

Taxane IC50 (nM)
Paclitaxel 2291 ± 125
1c 80.5 ± 7.6
1b-03 21.7 ± 2.3
SB-T-121205 (1a-05) 19.0 ± 2.0
SB-T-121405 (1c-05) 34.9 ± 3.0
SB-T-121605 (1d-05) 31.4 ± 2.8