Table 2. Patient characteristics and rs17576 genotype for both case and control patients.
| Characteristics | Case | Control | p | |
|---|---|---|---|---|
| N | 71 | 70 | ||
| Mean age (SD) | 49.99 (±12.03) | 45.38 (±12.77) | 0.071 | |
| Premenopausal | 40 | 46 | ||
| Mean age (SD) | 49.46 (±10.42) | 47.13 (±13.07) | 0.372 | |
| Postmenopausal | 31 | 24 | ||
| Mean age (SD) | 48.34 (±11.99) | 42.04 (±11.71) | 0.055 | |
| Case (%) | Control (%) | p | OR (95% CI) | |
|---|---|---|---|---|
| rs17576 | ||||
| AA | 35 (24.82) | 47 (33.33) | ||
| A/G | 26 (18.43) | 22 (15.60) | 0.2746 | 1.58 (0.73, 3.46) |
| GG | 10 (7.09) | 1 (0.70) | 0.0030 | 13.13 (1.73, 593.08) |
A significant difference was observed in the incidence of the rs17576 GG genotype between the case and control groups (p<0.003). The odds ratio (OR) was significantly higher in the case group.