Table 8. Interaction similarity scores of the selected HTL epitopes using GalexyPepDock flexible docking server.
Protein | Epitope | DRB1-0101 | DRB1-0301 | DRB1-0401 | DRB1-1101 | DRB1- 1501 | DRB5-0101 | Average* |
---|---|---|---|---|---|---|---|---|
S | NIDGYFKIYSKHTPINLVRDLPQGFS | 139 | 146 | 132 | 132 | 132 | 132 | 135.5 |
LKSFTVEKGIYQTSNFRVQPT | 124 | 126 | 124 | 126 | 124 | 126 | 125.0 | |
YQTSNFRVQPTESIVRFP | 118 | 105 | 118 | 118 | 108 | 118 | 114.1 | |
TQQLIRAAEIRASANLAATKMS | 133 | 123 | 113 | 123 | 113 | 113 | 119.6 | |
FTRGVYYPDKVFRSSVLHSTQD | 135 | 133 | 135 | 133 | 135 | 135 | 134.3 | |
PHGVVFLHVTYVPAQEKN | 170 | 128 | 128 | 128 | 132 | 128 | 135.6 | |
SQSIIAYTMSLGAENS | 141 | 129 | 141 | 141 | 141 | 141 | 139.0 | |
NFSQILPDPSKPSKRSF | 148 | 126 | 126 | 126 | 126 | 126 | 129.6 | |
YEPQIITTDNTFVSGNC | 123 | 116 | 120 | 116 | 123 | 120 | 119.6 | |
TQSLLIVNNATNVVIKV | 131 | 131 | 131 | 130 | 130 | 131 | 130.6 | |
M | RYRIGNYKLNTDHSSSSDNI | 117 | 113 | 117 | 117 | 117 | 117 | 116.3 |
SRTLSYYKLGASQRVAGDS | 124 | 124 | 124 | 128 | 124 | 128 | 125.3 | |
RSMWSFNPETNILLNVPLHGTI | 169 | 169 | 169 | 139 | 169 | 169 | 164.0 | |
DLPKEITVATSRTLSYYKL | 137 | 124 | 125 | 137 | 137 | 137 | 132.8 | |
N | GTWLTYTGAIKLDDKDPNFKDQ | 137 | 131 | 137 | 137 | 137 | 131 | 135 |
NKDGIIWVATEGALNTPK | 136 | 133 | 131 | 136 | 131 | 136 | 133.8 | |
KDPNFKDQVILLNKHIDAYK | 127 | 134 | 127 | 127 | 134 | 127 | 129.3 | |
NTASWFTALTQHGKED | 137 | 137 | 137 | 137 | 149 | 137 | 139.0 | |
LPKGFYAEGSRGGSQ | 107 | 107 | 107 | 105 | 105 | 107 | 106.3 | |
KQLQQSMSSADSTQA | 142 | 118 | 118 | 118 | 118 | 118 | 122.0 |
* Higher rates show better quality of modeling