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. 2020 Oct 15;15(10):e0240848. doi: 10.1371/journal.pone.0240848

Fig 1. Sox2 deletion in epithelial stem/progenitor cells results in the disappearance of taste buds.

Fig 1

Immunohistochemistry to marker proteins of taste bud cells in the circumvallate papillae (CvP) of Krt5CreERT2/+; Sox2flox/flox mice with and without tamoxifen injection (–Tam, control): SOX2 (top) and KCNQ1 (bottom) as a pan-taste bud cell marker. The broken lines show the boundary of epithelium and connective tissue. Number of analyzed mice was 3 at each point. Scale bar, 50 μm.