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. 2020 Sep 30;11:567191. doi: 10.3389/fgene.2020.567191

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Copyright © 2020 Aga, Hallahan, Gottmann, Jaehnert, Osburg, Schulze, Kamitz, Arends, Brockmann, Schallschmidt, Lebek, Chadt, Al-Hasani, Joost, Schürmann and Vogel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Insulin secretion in Nidd/DBA islets ex vivo. Glucose-stimulated insulin secretion (GSIS) in primary islets of 6 (n = 3) and 13 weeks old homozygous NZO (N/N, n = 4), heterozygous (N/D, n = 6), or homozygous DBA (D/D, n = 3) allele carriers for the Nidd/DBA locus (RCS-III, Nidd/DBA.6.3) with corresponding AUC (right panel). Data are presented as means ± SEM and were analyzed by one-way ANOVA.