Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Graphical abstract. UC-MSC are able to modulate monocyte differentiation toward M2-like macrophages via secretion of multiple cytokines to the extracellular media. Additionally, a concomitant action of induced M2-like macrophages and UC-MSC secretion of IL-2R and expression of PD-L1 and PDL-2 on the extracellular membrane produce regulation of activated CD3+ T cells, reducing the pool of effector cells and inducing terminally differentiated phenotype.
