TABLE 1.
Selected DEG involved in immune modulation by MSC.
| Ensembl gene ID | Gene | Category | C1 (TPM*) | C2 (TPM) | C3 (TPM) | C2/C1 |
| ENSG00000134460 | IL-2R | Pro-inflammatory cytokines | 0,24 | 41,20 | 0,38 | 170,89 |
| ENSG00000100368 | CD131 | Immunomodulation | 0,44 | 5,49 | 0,45 | 12,42 |
| ENSG00000277632 | MIP-1a | Chemokines | 2,43 | 18,89 | 0,70 | 7,77 |
| ENSG00000169245 | IP10 | Chemokines | 231,86 | 1.796,86 | 1,00 | 7,75 |
| ENSG00000131203 | IDO1 | Immunomodulation | 1.019,58 | 6.739,63 | 4,06 | 6,61 |
| ENSG00000136634 | IL-10 | Anti-inflammatory cytokines | 0,10 | 0,63 | 0,00 | 6,46 |
| ENSG00000135077 | Tim-3 | Immunomodulation | 4,69 | 24,00 | 4,73 | 5,11 |
| ENSG00000162692 | CD106 | Adhesion molecules | 470,45 | 2.262,98 | 323,86 | 4,81 |
| ENSG00000138755 | MIG | Chemokines | 2.975,08 | 13.407,50 | 8,90 | 4,51 |
| ENSG00000120217 | CD274 | Immunomodulation | 2.218,85 | 8.963,76 | 721,68 | 4,04 |
| ENSG00000164342 | TLR-3 | Immunomodulation | 90,33 | 358,27 | 44,51 | 3,97 |
| ENSG00000164400 | GM-CSF | Pro-inflammatory cytokines | 92,75 | 327,40 | 72,28 | 3,53 |
| ENSG00000090339 | CD54 | Adhesion molecules | 19.571,90 | 67.853,90 | 6.938,78 | 3,47 |
| ENSG00000136869 | TLR-4 | Immunomodulation | 4,34 | 14,56 | 2,78 | 3,36 |
| ENSG00000168811 | IL-12A | Pro-inflammatory cytokines | 22,85 | 67,73 | 16,43 | 2,96 |
| ENSG00000172156 | Eotaxin | Chemokines | 0,21 | 0,61 | 0,40 | 2,94 |
| ENSG00000064300 | CD271 | Immunomodulation | 6,89 | 18,19 | 3,80 | 2,64 |
| ENSG00000007171 | INOS | Immunomodulation | 11,40 | 28,95 | 0,59 | 2,54 |
| ENSG00000232810 | TNF | Pro-inflammatory cytokines | 0,75 | 1,88 | 0,27 | 2,51 |
| ENSG00000108342 | G-CSF | Growth factors | 1.282,41 | 3.092,31 | 892,93 | 2,41 |
| ENSG00000164136 | IL-15 | Pro-inflammatory cytokines | 182,61 | 436,09 | 157,91 | 2,39 |
| ENSG00000108691 | MCP1 | Chemokines | 2.766,09 | 6.329,78 | 2.195,54 | 2,29 |
| ENSG00000136689 | IL-1Ra | Anti-inflammatory cytokines | 3,26 | 6,53 | 3,34 | 2,00 |
| ENSG00000169429 | IL-8 | Pro-inflammatory cytokines | 31.530,40 | 62.329,00 | 32.269,30 | 1,98 |
| ENSG00000138685 | FGF-basic | Growth factors | 29.847,00 | 58.499,40 | 27.953,70 | 1,96 |
| ENSG00000170017 | ALCAM | Adhesion molecules | 2.834,57 | 5.541,63 | 2.820,10 | 1,96 |
| ENSG00000271503 | RANTES | Chemokines | 634,14 | 1.234,73 | 36,63 | 1,95 |
| ENSG00000112715 | VEGF | Growth factors | 11.938,60 | 21.878,40 | 9.581,04 | 1,83 |
| ENSG00000026508 | CD44 | Adhesion molecules | 9.061,18 | 16.467,30 | 9.987,75 | 1,82 |
| ENSG00000163739 | CXCL1 | Immunomodulation | 7.007,11 | 12.338,30 | 7.225,25 | 1,76 |
| ENSG00000136244 | IL-6 | Pro-inflammatory cytokines | 11.512,00 | 18.228,30 | 12.600,00 | 1,58 |
| ENSG00000125538 | IL-1b | Pro-inflammatory cytokines | 18.222,10 | 26.799,80 | 20.471,00 | 1,47 |
| ENSG00000113520 | IL-4 | Anti-inflammatory cytokines | 0,07 | 0,10 | 0,00 | 1,45 |
| ENSG00000103855 | CD276 | Immunomodulation | 2.553,27 | 1.670,55 | 2.904,12 | −1,53 |
| ENSG00000197919 | IFN-a | Anti-inflammatory cytokines | 46,50 | 22,77 | 73,31 | −2,04 |
| ENSG00000169439 | CD362 | Immunomodulation | 2.059,37 | 976,69 | 2.397,84 | −2,11 |
| ENSG00000113302 | IL-12B | Pro-inflammatory cytokines | 0,28 | 0,12 | 0,52 | −2,32 |
| ENSG00000076706 | CD146 | Immunomodulation | 1.400,11 | 531,04 | 1.400,00 | −2,64 |
| ENSG00000138798 | EGF | Growth factors | 325,45 | 100,18 | 465,06 | −3,25 |
| ENSG00000019991 | HGF | Growth factors | 1.219,34 | 272,46 | 1.266,22 | −4,48 |
| ENSG00000017427 | IGF1 | Immunomodulation | 28,20 | 1,59 | 32,35 | −17,75 |
*TPM, transcripts per million.