Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 7;9(10):bio053504. doi: 10.1242/bio.053504

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Fig. 1. — Lifespan, health and bacterial colonisation of the reference strain N2 in UV336 versus CBX102. (A) Lifespan analysis at 25°C showing that CBX102 (red) significantly reduced average survival calculated using the Mantel-Cox log-rank test, 95% confidence interval (CI) compared to UV336 and OP50. The latter strains were statistically indistinguishable (NS). (B) Rigorous movement (thrashing) of animals grown on OP50, UV336 or CBX102 as a proxy for health was calculated as the number of body bends per second (BBPS). Tukey's multiple comparisons with one-way ANOVA test was performed. Worms on CBX102 were significantly less mobile than on OP50 or UV336. These were again, NS. (C) Distributions for the fluorescence intensity of SYTO13 in the intestine of animals on OP50 (E. coli), UV336 (M. nematophilum, non-inflammatory strain) and CBX102 (M. nematophilum, pathogenic strain) at 25°C. *, results of two Tukey's multiple comparisons one-way ANOVA tests, 99% CI. All panels: ***P<0.0001; NS, non-significant; n=25 animals/treatments/group; results are from three independent experiments.