Table 7.

Pirfenidone serum concentrations

Pirfenidone serum levels	Fibrosis progression profile (FPP)	Fibrosis-stable profile (FSP)	Fibrosis regression profile (FRP)
Fasting sample (µg/mL)	4.7 ± 0.3	6.2 ± 1.4	8.2 ± 1.7a,b
2-h post-prandial sample (µg/mL)	8.2 ± 0.1	9.0 ± 1.3	9.3 ± 1.4

Statistical significance was analyzed by a generalized linear model with maximum likelihood as method of estimation and Bonferroni test

^ap < 0.01 compared to fibrosis progression profile subjects

^bp < 0.05 compared to fibrosis-stable profile subjects