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. 2020 Jun 30;14(5):828–841. doi: 10.1007/s12072-020-10068-4

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© The Author(s) 2020

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Fig. 6 — HMGB1 knockdown blocks the induction of autophagy as well as the attenuation of TG accumulation by p53 silencing in HepG2 and primary hepatocytes. a Western blotting results for Hmgb1-silenced primary hepatocytes from p53^+/+ and p53^−/− mice. b Western blotting results for HMGB1- and p53-silenced HepG2 cells. c, d Intracellular triglyceride levels and ORO staining in Hmgb1-silenced primary hepatocytes from p53^+/+ and p53^−/− mice with PA treatment for 24 h. e, f Intracellular triglyceride levels and ORO staining in HMGB1- and/or p53-silenced HepG2 cells treated with PA for 24 h. *p < 0.05, compared with the si-NC group; ^#p < 0.05, compared with the si-Hmgb1/si-HMGB1 group; NS no significance