Table 3.
Effect of taurine supplementation on biochemical markers in rats (mean ± SD)
| Parameter | Experimental group | ANOVA p value | |||||
|---|---|---|---|---|---|---|---|
| C | C + TAU | HF | HF + TAU | Diet | TAU | Diet × TAU interaction | |
| Glucose (mmol/L) | 7.75 ± 1.40 | 7.67 ± 1.67 | 9.51 ± 1.08 | 9.13 ± 1.68 | NS | NS | NS |
| Insulin (mIU/L) | 8.77 ± 1.76a | 9.33 ± 1.74a | 12.84 ± 3.07b | 9.84 ± 2.98ab | < 0.05 | < 0.05 | NS |
| HOMA-IR | 2.66 ± 0.65a | 2.93 ± 0.74a | 4.66 ± 0.89b | 3.88 ± 1.36ab | < 0.05 | < 0.05 | NS |
| Serum adiponectin (μg/L) | 2.31 ± 0.57 | 2.83 ± 0.88 | 2.11 ± 0.74 | 2.72 ± 0.92 | NS | NS | NS |
| Homocysteine (μmol/L) | 5.41 ± 1.76 | 5.35 ± 0.89 | 6.41 ± 2.25 | 5.02 ± 0.72 | NS | NS | NS |
| ALT activity (U/L) | 16.75 ± 2.05a | 16.60 ± 1.67a | 23.88 ± 5.77b | 18.57 ± 3.41ab | < 0.01 | NS | NS |
| AST activity (U/L) | 73.87 ± 12.90 | 74.80 ± 10.63 | 65.51 ± 9.58 | 68.71 ± 11.74 | NS | NS | NS |
| Urea (mmol/L) | 4.23 ± 0.61 | 4.55 ± 0.53 | 4.00 ± 0.45 | 4.61 ± 0.95 | NS | NS | NS |
| Creatinine (μmol/L) | 45.08 ± 3.54 | 44.20 ± 5.30 | 44.20 ± 4.42 | 45.97 ± 3.54 | NS | NS | NS |
Values are presented as means ± standard deviation; values in the row with different superscripts differ significantly (p < 0.05)
C rats fed standard diet (AIN-93M) control group, C + TAU rats fed standard diet (AIN-93M) supplemented with 3% taurine, HF rats fed high-fat diet, HF + TAU rats fed high-fat diet supplemented with 3% taurine, NS statistically non-significant difference