Table 5.

Effect of taurine supplementation on serum and tissular Cu concentration in rats (mean ± SD)

Parameter	Experimental group				ANOVA p value
	C	C + TAU	HF	HF + TAU	Diet	TAU	Diet × TAU interaction
Serum Cu (mmol/L)	16.13 ± 1.76b	13.48 ± 1.14ab	13.48 ± 0.68ab	12.09 ± 4.51a	NS	NS	NS
Hepatic Cu (μg/g d.m.)	18.47 ± 2.86b	17.71 ± 5.14b	12.14 ± 0.85a	12.40 ± 1.66a	< 0.0001	NS	NS
Renal Cu (μg/g d.m)	39.00 ± 9.33b	22.38 ± 5.46a	18.97 ± 4.02a	16.14 ± 3.23a	< 0.001	< 0.0001	< 0.01
Splenic Cu (μg/g d.m.)	8.14 ± 2.82	8.91 ± 3.65	8.00 ± 4.74	9.26 ± 3.83	NS	NS	NS
Cardiac Cu (μg/g d.m.)	20.47 ± 2.45b	18.96 ± 6.34ab	15.93 ± 2.81ab	13.96 ± 1.88a	< 0.05	NS	NS
Femur Cu (μg/g d.m.)	2.52 ± 0.76	2.71 ± 0.33	2.19 ± 0.41	2.45 ± 0.26	NS	NS	NS

Values are presented as means ± standard deviation; values in the row with different superscripts differ significantly (p < 0.05)

C rats fed standard diet (AIN-93M) control group, C + TAU rats fed standard diet (AIN-93M) supplemented with 3% taurine, HF rats fed high-fat diet, HF + TAU rats fed high-fat diet supplemented with 3% taurine, NS statistically non-significant difference