Table 1.
The list of differentially expressed cytokines (pg/ml)
| Pre-SCI | 1 dpi | 3 dpi | 7 dpi | 14 dpi | 21 dpi | |
|---|---|---|---|---|---|---|
| IL-10 | 74.04 ± 41.92 | 20.67 ± 19.14**** | 83.66 ± 34.80 | 130.09 ± 49.57 | 176.79 ± 120.53 | 74.38 ± 40.19 |
| EPO | 1011.78 ± 830.46 | 1009.3 ± 666.14 | 552.78 ± 188.21 | 522.78 ± 250.49 | 7613.48 ± 1308.58**** | 9146.79 ± 700.23**** |
| MIP 1β | 65.39 ± 60.59 | 49.29 ± 30.43 | 38.55 ± 26.19 | 59.96 ± 22.60 | 849.71 ± 109.22**** | 1062.1 ± 207.89**** |
| GM-CSF | 9.41 ± 6.77 | 11.36 ± 14.67 | 30.89 ± 14.11 | 50.40 ± 16.31** | 37.38 ± 16.83 | 21.10 ± 11.84 |
| GASP 1 | 2082.21 ± 564.18 | 1834.3 ± 224.79 | 1202.59 ± 266.79* | 2080.71 ± 639.20 | 2582.31 ± 186.45 | 2692.17 ± 282.30 |
| FGF7 | 38.87 ± 48.56 | 43.87 ± 59.20 | 34.84 ± 20.52 | 25.24 ± 11.72 | 153.34 ± 70.31* | 105.40 ± 50.63 |
| TNF R1 | 4.55 ± 9.10 | 1.79 ± 3.57 | 10.61 ± 18.01 | 11.53 ± 23.06 | 279.21 ± 163.72*** | 197.44 ± 108.16* |
| NOPE | 4242.31 ± 1871.29 | 1763.04 ± 628.61 | 1652.22 ± 1186.37* | 2735.73 ± 839.79 | 2938.60 ± 1039.98 | 3439.99 ± 963.74 |
| IFNγ | 1.76 ± 3.52 | 38.29 ± 15.31 | 0.00 ± 0.00 | 0.00 ± 0.00 | 537.70 ± 14.19**** | 584.86 ± 56.55**** |
| IL-1α | 52.01 ± 61.16 | 23.54 ± 17.05 | 51.48 ± 44.15 | 26.81 ± 20.17 | 394.88 ± 109.51**** | 522.24 ± 110.69**** |
| IL-1β | 91.82 ± 55.51 | 121.18 ± 23.85 | 149.08 ± 116.42 | 86.20 ± 56.11 | 177.42 ± 17.38 | 310.04 ± 146.17* |
| IL-17A | 13.32 ± 24.18 | 18.61 ± 22.19 | 8.93 ± 10.06 | 21.65 ± 36.92 | 394.73 ± 404.11 | 560.61 ± 282.52** |
Compared with baseline expression level of pre-SCI dogs. Data are presented as mean ± SD, n = 5 in each group, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001