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. 2020 Oct 15;11(10):859. doi: 10.1038/s41419-020-03078-5

Fig. 6. BMP4 Tg expression reduces maternal diabetes-induced apoptosis in the developing neuroepithelium.

Fig. 6

a Representative TUNEL staining images showing apoptotic cells (red dots) in the E8.5 neuroepithelium. Cell nuclei were stained with DAPI (blue), Scale bar = 30μm. Quantification of TUNEL positive cells per section was shown in the graph. b Protein levels of cleaved caspase 8 and caspase 3 in E8.5 embryos. Experiments were performed using three embryos from three different dams per group (n = 3). * indicates significant difference compared to the other groups (P < 0.05) in one-way ANOVA followed by Tukey tests. ND: nondiabetic; DM: diabetes mellitus.