Table 2. Biochemical, virologic and serologic responses at week 24 and week 48.

	Week 24				Week 48
Variables	Combination group	Control group	p-value		Combination group	Control group	p-value
N (Miss)	25	26			23 (2)	25 (1)
ALT, IU/L	32.80±12.08	37.03±15.96	0.29		30.97±12.18	33.92±20.00	0.54
Virologic response*	19 (76.0%)	21 (80.8%)	0.68		21 (91.3%)	23 (92.0%)	1.00
Baseline HBeAg(+) N (Miss)	15	14			13 (2)	14 (0)
HBeAg loss	4 (26.7%)	4 (28.6%)	1.00		4 (30.8%)	5 (35.7%)	1.00
HBeAg seroconversion	3 (20.0%)	4 (28.6%)	0.68		1 (7.7%)	4 (28.6%)	0.33

^*Virologic response was defined as serum HBV DNA <500 IU/mL.

Abbreviations: ALT, alanine aminotransferase; HBeAg, hepatitis B e antigen.