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. 2020 Jul 21;8(3):277–284. doi: 10.14218/JCTH.2020.00004

Table 3. Collagen parameters with significant changes.

Variables Week 0 Week 48 p-value
Combination group
Portal collagen fiber number 238.51 (176.18∼405.88) 207.12 (101.67∼303.67) 0.038
Type I collagen fiber number 179.83 (125.31∼317.71) 166.13 (102.02∼234.70) 0.021
Type III collagen fiber number 48.33 (34.34∼83.67) 39.04 (22.33∼55.86) 0.045
Type IV collagen fiber number 188.48 (145.29∼304.74) 183.28 (112.57∼249.55) 0.043
Portal distributed collagen proportionate area 224.20 (163.89∼382.37) 202.04 (146.95∼285.08) 0.038
Portal collagen fiber curvature 161.92 (117.31∼275.08) 144.74 (89.31∼207.09) 0.033
Percentage of type II perivascular collagen 0.09 (0.05∼0.14) 0.04 (0.03∼0.09) 0.007
Perivascular collagen fiber total number 212.07 (135.57∼297.50) 137.17 (75.49∼199.40) 0.017
Perivascular type I collagen fiber number 161.05 (106.26∼226.50) 100.82 (70.67∼149.00) 0.009
Perivascular type III collagen fiber number 43.45 (26.38∼57.07) 26.51 (20.81∼34.98) 0.014
Perivascular type IV collagen fiber number 169.21 (113.46∼232.02) 106.07 (60.73∼171.40) 0.020
Perivascular collagen fiber length 10143 (5899∼12753) 7179 (4306∼11601) 0.048
Perivascular type I collagen fiber total number 206.53 (131.94∼284.00) 141.46 (94.54∼216.00) 0.026
Perivascular I-I collagen fiber number 156.24 (102.99∼213.75) 100.23 (70.00∼145.20) 0.017
Perivascular I-III collagen fiber number 41.71 (25.18∼55.90) 25.63 (18.64∼33.50) 0.025
Perivascular I-IV collagen fiber number 167.36 (113.26∼226.33) 105.99 (59.83∼169.20) 0.030
Perivascular collagen cross-link density 5315 (3351∼8643) 3183 (1856∼5559) 0.040
Control group
Percentage of perivascular collagen 1.26 (0.84∼1.98) 0.56 (0.42∼1.27) 0.013
Percentage of type I perivascular collagen 1.19 (0.77∼1.83) 0.51 (0.36∼1.22) 0.015