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. 2020 Oct 15;10:17345. doi: 10.1038/s41598-020-74413-1

Table 2.

Pearson’s correlation analysis and multiple regression analysis of CTRP-1 during pregnancy.

Pregnancy All (in pregnancy) GDM (in pregnancy) NGT (in pregnancy)
Simple Multiple regression Simple Multiple regression Simple Multiple regression
RP P β P RP P β P RP P β P
Week of gestation 0.000 0.996 − 0.044 0.629 0.038 0.626
Weight − 0.173 0.003 − 0.065 0.393 − 0.139 0.122 − 0.199 0.011 − 0.038 0.773
Height 0.084 0.154 0.135 0.135 0.026 0.743
Waist 0.056 0.572 − 0.039 0.816 0.059 0.637
Hip 0.028 0.781 0.143 0.391 − 0.063 0.614
Age 0.009 0.880 0.078 0.390 − 0.031 0.696
RR systolic 0.015 0.807 − 0.002 0.985 0.053 0.504
RR diastolic − 0.057 0.332 − 0.077 0.394 − 0.011 0.887
Matsuda Index 0.269  < 0.001 − 0.048 0.672 0.353 0.001 0.136 0.415 0.210 0.011 0.125 0.580
Stumvoll first phase index − 0.257  < 0.001 − 0.145 0.156 − 0.241 0.028 − 0.105 0.442 − 0.335  < 0.001 − 0.281 0.212
ISSI-2 0.218 0.001 0.258 0.003 0.256 0.021 0.146 0.291 0.159 0.056 − 0.041 0.813
AUC insulin − 0.213 0.001 − 0.106 0.322 − 0.226 0.040 0.075 0.691 − 0.181 0.029 0.118 0.602
AUC glucose 0.009 0.894 0.093 0.406 0.117 0.160
HbA1c 0.160 0.006 0.156 0.027 0.259 0.004 0.238 0.018 0.119 0.130
Adiponectin 0.098 0.182 0.092 0.384 0.070 0.496
usCRP − 0.079 0.184 0.019 0.836 − 0.168 0.032 − 0.034 0.802
Estradiol − 0.048 0.419 − 0.080 0.377 − 0.027 0.736
Bioavailable estradiol − 0.122 0.039 − 0.045 0.515 − 0.240 0.007 − 0.280 0.008 − 0.015 0.849
Testosterone − 0.083 0.316 0.131 0.315 − 0.279 0.009 − 0.255 0.042
Bioavailable testosterone − 0.058 0.488 0.153 0.243 − 0.210 0.057 − 0.533 0.063

All variables with p < 0.1 were included in the multiple regression analysis to test the joint effect of these parameters on CTRP-1. Variables with a VIF > 3.5 in the multicollinearity diagnostic were excluded from the analysis.

Bold indicates the significance level is p < 0.05.