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. 2020 Oct 15;10:17480. doi: 10.1038/s41598-020-74623-7

Table 1.

Common candidate genes associated with EGCG and caffeine contents as assessed by genome-wide association studies (GWASs).

Associated SNPs Candidate genes
GeneID Chr Gene position (bp) Strand Distance from gene (bp) Gene annotation
Chr Position (bp) P-value for EGCG P-value for caffeine Up Down
12 2,549,738 3.E−05 2.E−03 CSS0013722 12 2,544,002 2,563,160 Region within the gene Putative phagocytic receptor 1b
4 71,890,059 1.E−02 6.E−03 CSS0006445 4 71,892,372 71,894,683 2313 NA
14 87,255,362 7.E−03 2.E−02 CSS0007093 14 87,257,768 87,260,368  +  − 2406 Hypothetical protein VITISV_023007
2 12,909,634 2.E−03 7.E−03 CSS0008055 2 12,908,731 12,917,237 Region within the gene Probable serine/threonine-protein kinase
7 26,653,857 1.E−02 2.E−02 CSS0012938 7 26,645,975 26,689,027  +  Region within the gene SPA1-related 3 isoform 1
15 5,519,341 8.E−03 2.E−02 CSS0014189 15 5,518,230 5,522,057 Region within the gene RING-H2 finger protein ATL3
4 71,890,059 1.E−02 6.E−03 CSS0020256 4 71,881,294 71,884,993  +  5066 Auxin response factor 17-like
1 217,617,856 8.E−03 2.E−02 CSS0023674 1 217,618,798 217,622,981 942 Hypothetical protein VITISV_013519
15 5,519,341 8.E−03 2.E−02 CSS0025062 15 5,502,746 5,516,691  +  2650 Ubiquitin conjugating enzyme J2
14 79,981,575 3.E−03 4.E−03 CSS0026002 14 79,978,507 79,982,432 Region within the gene MATE efflux family protein 5
2 12,909,634 2.E−03 7.E−03 CSS0029046 2 12,894,561 12,904,995 − 4639 Proteasome subunit alpha type-2-B
4 71,890,059 1.E−02 6.E−03 CSS0030407 4 71,894,597 71,901,185  +  − 4538 Auxin response factor 17-like
2 12,909,634 2.E−03 7.E−03 CSS0050267 2 12,915,964 12,922,795 6330 WRKY transcription factor