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System-specific contacts that contribute more than 1% of flux to the TM6 movement in A) methadone-, B) morphine-, and C) TRV130-bound MOR systems. Contacts (depicted as lines) that are common among all three systems or between any two systems (as highlighted in Supplemental Table 9) are not shown. Low-to-high contribution values (0, 0.25) are color-coded from light cyan to magenta.
