Figure 3.

Differentially identified genes from the meta-analysis of SS and L-HES are supported by prior SS studies. Gene expression results from Moerman-Herzog et al. were compared to prior transcriptomic profiling studies of SS (Table 3). Genes differentially expressed from SS of prior studies were identified from the manuscript and supplementary data, using the significance threshold defined by each study. Gene symbols were updated using the Molecular Signatures database [79] and/or the GeneCards database [80]. Gene groups are defined by expression pattern, (A) upregulated SS-unique genes, (B) downregulated SS-unique genes, (C) upregulated shared genes, (D) downregulated shared genes. Only genes reported in at least three studies are shown. For each gene, studies that reported significant differential expression for that gene are represented by color-coded boxes next to the gene symbol.