Table 3.
Meta-Analysis Study | Sézary Patients | Healthy Donors | BID | Technology |
Moerman-Herzog et al. [22] | n = 3 CD3+CD4+CD45RO+ |
n = 3 CD3+CD4+CD45RO+ |
n.a. | microarray |
Prior Study | Sézary Patients | Healthy Donors | BID | Technology |
Fanok et al. [73] | n = 8 CD3+CD4+CD7−
and/or CD3+CD4+CD26− |
n =4 CD3+CD4+CD45RO+ | n.a. | RNAseq |
Wang et al. [68] | n = 22 CD3+CD4+ | n = 5 CD3+CD4+ | n.a. | RNAseq |
Wysocka et al. [78] | n = 6 CD3+CD4+ | n = 3 CD3+CD4+ | n.a. | microarray |
Wang et al. [72] | n = 6 CD3+CD4+CD7- | n = 9 CD3+CD4+ | n.a. | microarray |
Booken et al. [16] | n = 10 PBMC | n =10 PBMC | n.a. | microarray |
Hahtola et al. [17] | n = 4 PBMC | n = 5 PBMC | n.a. | microarray |
van Doorn et al. [14] | n = 10 CD3+CD4+ | n = 3 CD3+CD4+ | n = 5 CD3+CD4+ | microarray |
Kari et al. [71] | n = 18 >60% CD4+ |
n = 12 Th2-skewed PBMC |
n.a. | microarray |
Prior Study | Sézary Malignant Cells |
Patient-Matched
Non-Malignant Cells |
BID | Technology |
Borcherding et al. [74] | n = 1 CD3+CD4+CD5brightSSChi |
n = 1 CD3+CD4+CD5intSSCint |
n.a. | scRNAseq |
Lee et al. [75] | n = 3 CD3+CD4+Vβ+ |
n = 3 CD3+CD4+Vβ− |
n.a. | RNAseq |
n.a., not applicable; RNAseq, RNA sequencing; scRNAseq, single cell RNAseq.