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. 2020 Aug 19;12(9):2343. doi: 10.3390/cancers12092343

Figure 5.

Figure 5

OS and EFS of clinically relevant sub-groups of patients stratified by the NB-hop classifier. Kaplan-Meier curves show OS and EFS of NB patients in the test set predicted by NB-hop classifier. Plots are relative to (A) high-risk patients, stage 4, and age > 18 months, (B) intermediate-risk patients, stage 4, age < 18 months, and with not amplified MYCN tumors, (C) low-risk patients with stages 1, 2, 4s and no MYCN amplification tumor, (D) intermediate-risk patients, age > 18 months, stage 3 with not amplified MYCN tumors. Plots are entitled with the characteristics of the patients in the sub-population. F NB-hop (blue) and UF (red) curves were compared by approximate log-rank test or exact log-rank test when approximate log-rank p value <0.0001 or >0.0001, respectively. Each plot reports the HR and 95% CI. Number of patients classified as F or UF (brackets), and the number of patients who succumbed to disease or underwent an event (square brackets) are reported. OS: Overall survival; EFS: Event-free survival; HR: hazard ratio; CI: confidence interval; F: favorable; UF: Unfavorable.