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. 2020 Sep 4;10(9):1281. doi: 10.3390/biom10091281

Figure 6.

Figure 6

Schematic diagram of SMAD4/miR-361-5p/VEGFA regulatory signaling in porcine GCs. SMAD4 negatively regulates MIR361 transcription by binding to the MIR361 promoter, while matured miR-361-5p reduces VEGFA expression level by directly binding to 3′UTR VEGFA mRNA.