Table 1.
Specific function and wound type targets for different electrospun biopolymer dressings.
| Electrospun Mesh | Incorporated Therapeutics | Function & Wound Type | References |
|---|---|---|---|
| Cellulose acetate (CA)/Manuka honey (MH) | - | Antibacterial activity for infection in the burn wounds | [37] |
| CA/polyester urethane | Polyhexamethylene biguanide (PHMB) | Antimicrobial activity | [110] |
| Chitosan/bacterial nano cellulose | - | Antimicrobial properties | [122] |
| Chitosan/silk fibroin | - | Antibacterial properties Acute wounds |
[121] |
| Chitosan/sericin | - | Biocompatibility and antibacterial properties | [120] |
| Chitosan/Poly (l-lactide) (PLLA) | Graphene oxide | Antimicrobial activities for chronic infected wounds | [50] |
| Chitosan/keratin/polycaprolactone (PCL) | Aloevera extract | Anti-inflammatory, antibacterial, antiviral, and antioxidant properties for acute and burn wounds | [35] |
| Chitosan/Polyvinyl alcohol (PVA) | Nanobioglass (nBG) | Biocompatibility, antibacterial activity and regeneration promotion effect for chronic wound | [5] |
| Gelatin/Oleoyl chitosan | - | Large skin defects or chronic wounds | [123] |
| Polyhydroxyalkanoate (PHA) | Dodecyltrimethylammonium chloride (DTAC) biocide | Antimicrobial effects for chronic wounds | [160] |
| PHA | Graphene/decorated silver nanoparticles (GAg) | Antimicrobial activity for chronic wounds | [141] |
| Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) | Cerium Oxide Nanoparticle | Antioxidant and angiogenic properties Diabetic wounds |
[8] |
| PHBV | Cerium oxide nanoparticles (nCeO2) | Antioxidant and angiogenic properties for diabetic wounds | [8] |
| PHBV | Curcumin | Antioxidant, anti-inflammatory, and antitumor properties chronic wounds including burns, diabetic foot ulcers, venous leg ulcers, and pressure ulcers | [39] |
| PHBV/cellulose | ZnO nanocrystals | Antibacterial activity for acute and infected wounds | [154] |
| Polylactides (PLA) | AgNPs | Antimicrobial activity for burn wounds and diabetic ulcers | [87] |
| PLA | Curcumin, Enrofloxacin | Antioxidant activity, antimicrobial activity, and biocompatibility | [70] |
| PLA | Doxycycline (DCH) | Antibacterial activity, Chronic wounds, diabetic wounds | [42] |
| PLA | Silver (I) metal–organic framework Ag2[HBTC][im] | Antibacterial feature | [10] |
| PLLA | Curcumin | Anti-inflammatory antioxidant effects | [166] |
| PLA/hyperbranched polyglycerol (HPG) | Curcumin | Antioxidant, anti-inflammatory and anti-infective properties for acute and chronic wound | [31] |
| PLA/PVA | Connective tissue growth factor (CTGF) | Diabetic wounds | [165] |
| poly(lactic-co-glycolic acid) (PLGA)/gelatin | Recombinant human epidermal growth factor (rhEGF), gentamicin sulfate | - Antibacterial activity and rhEGF supply - Diabetic wound |
[90] |
| PLGA/polydopamine | Basic fibroblast growth factor (bFGF), ponericin G1 | Antibacterial and cell proliferation-promoting properties for skin tissue regeneration | [89] |